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Chronic Kidney Disease Linked to Reflux Medicines


Chronic kidney disease has been linked to Prilosec, Prevacid and Nexium, common medicines used for heartburn and acid reflux by millions of people. Many people who suffered serious kidney-related side effects have filed personal injury claims with a product liability attorney to seek damages.

Research Studies Raise Safety Concerns

Recent medical studies conducted by Washington University School of Medicine in St. Louis show growing evidence that heartburn and acid reflux medicines are linked to kidney-related illness. Studies report that Prilosec, Prevacid and Nexium, popular medicines used for heartburn and acid reflux, are linked to serious kidney-related illnesses including:

  • Chronic Kidney Disease
  • Acute Interstitial Nephritis
  • Severe Renal Impairment
  • Acute Kidney Injury
  • End-Stage Renal Disease
  • Renal and Kidney Failure

Research studies show that more 50 percent of patients who developed chronic kidney damage while using these drugs did not show any signs of severe kidney problems before being diagnosed with chronic kidney disease. For this reason, these drugs have been referred to as having serious "silent side effects" for many users. Research studies raise concerns that the use of these drugs can cause undetected problems that gradually erode kidney function and lead to long-term kidney damage or renal failure without warning signs.

During the course of the studies and follow up with patients, researchers discovered that over 80 percent of people who used these drugs showed no signs of acute kidney problems, which are often reversible when caught in time. More than 50 percent of the cases of chronic kidney disease and end-stage renal disease, a life-threatening condition which requires kidney dialysis or a kidney transplant, occurred in people without any signs of medical complications including acute kidney problems.

Research study results suggest that long-term use of proton pump inhibitors (PPIs) increase the risk of developing chronic kidney disease and the progression to complete kidney failure. Findings emphasize that PPI use should be limited to medical necessity and used only for short durations of time.

According to health care statistics, approximately 15 million Americans were prescribed proton pump inhibitors (PPIs) in 2013. This number is likely underestimated because some medications are also available over-the-counter and can be purchased without a prescription.

Due to the severity of complications caused by drugs like Prilosec, Prevacid and Nexium, millions of personal injury claims have been filed throughout the country with a product liability attorney, and many more people are investigating possible product liability lawsuits against the responsible pharmaceutical companies.

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